Protocol Overview

Logic Diagram

Overall aim: Accelerate the identification of drugs for patients with sepsis through an international phase 2
precision medicine platform trial.

Equality, Diversity and Inclusion Strategy for the TIGERS platform trial - DRAFT

Intervention Prioritisation Plan for the TIGERS Platform Trial – DRAFT

Biological sampling / biobanking summary for TIGERS trial – DRAFT

Early / Mid Career Research Capacity Building Plan – DRAFT

Simulation Report - version 1.2

November 21st, 2025

Simulation Report - version 1.0

Supplementary Material:
Sensitivity analyses

July 9th, 2025